This case study focuses on the Maxillofacial Surgery Service, where computer-assisted surgery is used to enhance reconstructive and orthognathic procedures aimed at correcting cranioencephalic deformities. The integration of technology, including 3D imaging reconstruction and mapping, multimodal image-fusion technology, and CAD/CAM, allows for preoperative virtual planning of tumour excision and reconstruction. The surgical team uses software to simulate both 2D and 3D reconstructions, designing cutting guides and implants to evaluate the desired final outcome. Cutting guides are then manufactured using 3D printing, and during the surgery, a navigation system supported by intraoperative imaging ensures precise resection and reconstruction, closely matching the preoperative simulations. These orthognathic surgeries are typically scheduled almost every week.